Blu-ray LED belly can accurately control blood sugar

The use of drugs to adjust insulin in people with diabetes is a common way to control blood sugar, but it is often because the drug is too fierce to make blood glucose transiently too low, or it may cause damage to the brain or heart. Scholars have studied the use of blue LEDs to irradiate medicines in the body so that they can be turned "on" or "off", and they can regulate insulin in a more precise way and reduce harm to the body. The study was published in the journal Nature Communications.

The study was jointly developed by the Imperial College London, England, and the University of Munich, Germany. They modified a drug "Sulfonylurea," which is already in use, so that it could change shape through blue LED illumination, that is, After the diabetic patient eats the modified drug JB253, it will not have an immediate effect (upper left in the figure above). When he takes the blue LED onto the skin (above in the image above), it will change the shape of the drug (above right ), And start the drug began to stimulate the body to release insulin, when the LED light turned off, the drug returned to its original shape, it will stop working (in the figure below).

David Hodson, MD, MD, PhD, of the Imperial College School of Medicine, said that in addition to regulating how much insulin is switched on and off, this approach can also reduce some complications by allowing the drug to start functioning on a specific part of the body, such as the pancreas (bottom left). . He also emphasized that this study is still an early stage, and it will take some time before it can truly develop the available therapies.